Metathetic sulfur transfer mediated by N-(2-aminophenyl)-4-methyl-thiazolin-2-thione derivatives: a route to diversely substituted S-alkylcarbamothioates
…, MA Mehdid, A Djafri, F Andreoli, N Vanthuyne…
Index: Doukara, Abdallah Larbi; Mehdid, Mohammed Amine; Djafri, Ayada; Andreoli, Federico; Vanthuyne, Nicolas; Roussel, Christian Tetrahedron, 2010 , vol. 66, # 10 p. 1852 - 1858
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Citation Number: 3
Abstract
A new route to S-alkylcarbamothioates is disclosed. In a first step, N-(2-aminophenyl)-4- methyl-thiazolin-2-thione is transformed into a mono-or disubstituted urea at nitrogen, and then in a second step, alkylated at sulfur. The resulting salts, after treatment with a base, gave S-alkylcarbamothioates in high isolated yields together with 3-methyl [1, 3] thiazolo [3, 2-a] benzimidazole under very mild conditions.
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