Synthesis

Titanocene-catalyzed reductive epoxide opening: The quest for novel hydrogen atom donors

A Gansaeuer, A Barchuk, D Fielenbach

Index: Gansaeuer, Andreas; Barchuk, Andriy; Fielenbach, Doris Synthesis, 2004 , # 15 p. 2567 - 2573

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Citation Number: 15

Abstract

Abstract Novel hydrogen atom donors for the reductive titanocene-catalyzed epoxide opening are presented. While the potentially attractive cyclopentadienes gave only moderate yields of the desired alcohols, substituted, nontoxic, and commercially available 1, 4-cyclohexadienes, eg γ-terpinene, in combination with more elaborate catalysts gave better or similar results than the much more expensive and carcinogenic 1, 4-cyclohexadiene. In ...