A Direct Amine??Palladium Acetate Cocatalyzed Saegusa Oxidation Reaction of Unmodified Aldehydes to α, β??Unsaturated Aldehydes

J Zhu, J Liu, R Ma, H Xie, J Li, H Jiang…

Index: Zhu, Jin; Liu, Jie; Ma, Ruoqun; Xie, Hexin; Li, Jian; Jiang, Hualiang; Wang, Wei Advanced Synthesis and Catalysis, 2009 , vol. 351, # 9 p. 1229 - 1232

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Citation Number: 43

Abstract

Abstract: A direct preparation of synthetically useful α, β-unsaturated aldehydes from readily available aldehydes has been developed. The process is effectively cocatalyzed by an amine-palladium acetate to give rise to α, β-unsaturated aldehydes in moderate to good yields (41–62%). The reaction features the use of unmodified aldehydes rather than enol silyl ethers, which are used in a typical Saegusa oxidation reaction. Keywords: ...