Journal of Medicinal Chemistry

Central Nervous System Depressants--II. 4-Allyloxy-3, 5-dialkylbenzoic Acids and Derivatives

RB Moffett, PH Seay

Index: Moffett,R.B.; Seay,P.H. J. Med. Pharm. Chem., 1960 , vol. 2, p. 201 - 212

Full Text: HTML

Citation Number: 2

Abstract

The high activity of 4-allyloxy-3, 5-dipropylbenzoic acid and certain of its derivatives (I) in increasing the sleeping time of mice given small doses of hexobarbital1 has encouraged us to prepare a number of analogues in which methyl, ethyl, or isopropyl substituents replace the two propyl groups (11). In general these

Related Articles:

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping

[Deng, Jing; Li, Ning; Liu, Hongchuan; Zuo, Zhili; Liew, Oi Wah; Xu, Weijun; Chen, Gang; Tong, Xiankun; Tang, Wei; Zhu, Jin; Zuo, Jianping; Jiang, Hualiang; Yang, Cai-Guang; Li, Jian; Zhu, Weiliang Journal of Medicinal Chemistry, 2012 , vol. 55, # 14 p. 6278 - 6293]

More Articles...