Tetrahedron letters

Conjugate addition of copper (I) aldimines to α, β-unsaturated carbonyl compounds—synthesis of 1, 4-diketones

Y Ito, H Imai, T Matsuura, T Saegusa

Index: Ito, Yoshihiko; Imai, Hiroshie; Matsuura, Takaharu; Saegusa, Takeo Tetrahedron Letters, 1984 , vol. 25, # 29 p. 3091 - 3094

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Citation Number: 18

Abstract

Abstract This paper describes the finding that BF 3 etherate effectuates the conjugate additions of copper (I) aldimines, generated in situ from lithium aldimines and Cu (I) halide, to α, β-unsaturated carbonyl compounds to produce 4-(N-alkylimino)-ketones, which give on acid hydrolysis 1, 4-diketone derivatives.

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