Heteroatom Chemistry

Synthesis and antivirus activity of 1, 3, 5??triazine derivatives

Q Wang, G Liu, R Shao, R Huang

Index: Wang, Qingmin; Liu, Gang; Shao, Ruilian; Huang, Runqiu Heteroatom Chemistry, 2003 , vol. 14, # 6 p. 542 - 545

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Citation Number: 6

Abstract

Abstract Reaction of 6-phenyl-4-thioxo-1, 3, 5-triazine-2-one with alkyl halide in the presence of 1 equiv. of sodium hydroxide resulted in 4-alkylthio-6-phenyl-1, 3, 5-triazine-2- one in good yield, whereas the above reaction provided 2-alkoxyl-4-alkylthio-6-phenyl-1, 3, 5-triazine in the presence of 2 equiv. of sodium hydroxide. 6-Phenyl-4-thioxo-1, 3, 5-triazine- 2-one was oxidized with hydrogen peroxide to give 6-phenyl-1, 3, 5-triazine-2, 4-dione. ...