The rhodium carbenoid route to oxazoles. Synthesis of 4-functionalised oxazoles; Three step preparation of a bis-oxazole
KJ Doyle, CJ Moody
Index: Doyle, Kevin J.; Moody, Christopher J. Tetrahedron, 1994 , vol. 50, # 12 p. 3761 - 3772
Full Text: HTML
Citation Number: 76
Abstract
Oxazole-4-sulfones,-phosphonates, and-nitriles are prepared by rhodium (II) catalysed addition of nitriles to the corresponding diazo compound. The effect of the ligand on rhodium was briefly investigated, with rhodium (II) trifluoroacetamide generally proving the most effective catalyst. The 4-cyanooxazole 9 is readily converted into the bis-oxazoles 10–12.
Related Articles:
[Charrier, Josiane; Foucaud, Andre'; Person, Herve'; Loukakou, Emile Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 481 - 486]
[Charrier, Josiane; Foucaud, Andre'; Person, Herve'; Loukakou, Emile Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 481 - 486]
Tri??and Tetrasubstituted N??Phthalimidoaziridines in 1, 3??Dipolar Cycloaddition Reactions
[Ushkov, Alexander V.; Kuznetsov, Mikhail A.; Linden, Anthony; Heimgartner, Heinz Helvetica Chimica Acta, 2010 , vol. 93, # 5 p. 847 - 862]
[Charrier, Josiane; Foucaud, Andre'; Person, Herve'; Loukakou, Emile Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 481 - 486]
[Charrier, Josiane; Foucaud, Andre'; Person, Herve'; Loukakou, Emile Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 481 - 486]