Synthesis and antimalarial testing of neocryptolepine analogues: Addition of ester function in SAR study of 2, 11-disubstituted indolo [2, 3-b] quinolines

WJ Lu, KJ Wicht, L Wang, K Imai, ZW Mei…

Index: European Journal of Medicinal Chemistry, , vol. 64, p. 498 - 511

Full Text: HTML

Citation Number: 27

Abstract

... European Journal of Medicinal Chemistry. ... for the treatment of malaria patients [4]. The unique endoperoxide structure of artemisinin emerged in the 1970s as the results of efforts to find a new drug from plants [5]. These drugs are still important regarding medical treatment and ...

Related Articles:

Simple, fast and efficient synthesis of β-keto esters from the esters of heteroaryl compounds, its antimicrobial study and cytotoxicity towards various cancer cell lines

[Venkat Ragavan; Vijayakumar; Rajesh; Palakshi Reddy; Karthikeyan; Suchetha Kumari Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4193 - 4197]

Tandem Michael addition-[3, 3] sigmatropic rearrangement processes: a concise route to functionalized 3-alkoxycarbonylindoles

[Heterocycles, , vol. 31, # 8 p. 1431 - 1433]

Preparation of 3, 4-enynoindoles via directed lithiation and application to the synthesis of 3, 4-carbocycloindoles

[Perez-Serrano, Leticia; Casarrubios, Luis; Dominguez, Gema; Freire, Guillermo; Perez-Castells, Javier Tetrahedron, 2002 , vol. 58, # 27 p. 5407 - 5415]

Palladium-Catalyzed Oxidative C–N Bond Coupling Involving a Solvent-Controlled Regioselective Bromination Process

[Ji, Xiaochen; Huang, Huawen; Wu, Wanqing; Li, Xianwei; Jiang, Huanfeng Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11155 - 11162]

Desulfonylation of Indoles and 7-Azaindoles Using Sodium tert-Butoxide

[Chaulet, Charlotte; Croix, Cecile; Basset, Joan; Pujol, Maria-Dolores; Viaud-Massuard, Marie-Claude Synlett, 2010 , # 10 p. 1481 - 1484]

More Articles...