Stereoselective dichlorination of allylic alcohol derivatives to access key stereochemical arrays of the chlorosulfolipids

…, JS Kanady, CD Vanderwal

Index: Shibuya, Grant M.; Kanady, Jacob S.; Vanderwal, Christopher D. Journal of the American Chemical Society, 2008 , vol. 130, # 37 p. 12514 - 12518

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Citation Number: 61

Abstract

Dichlorination of (Z)-allylic trichloroacetates efficiently and stereoselectively generates the syn, syn hydroxydichloride stereotriad that is prevalent in the understudied polychlorinated sulfolipid class of natural products. Further, the dichlorination of a (Z)-allylic chlorohydrin ...