Synthesis, structural characterization, crystallographic analysis and antibacterial properties of some nitrofuryl triazolo [3, 4-b]-1, 3, 4-thiadiazines

…, B Kalluraya, KR Sridhar, E Drake, LM Thomas…

Index: Holla, B. S.; Kalluraya, B.; Sridhar, K. R.; Drake, E.; Thomas, L. M.; et al, European Journal of Medicinal Chemistry, 1994 , vol. 29, # 4 p. 301 - 308

Full Text: HTML

Citation Number: 96

Abstract

Abstract A series of 1-(5-nitro-2-furyl)-2-bromo-3-aryl-2-propen-1-ones has been prepared through dehydrobromination of 2, 3-dibromo-1-(5-nitro-2-furyl)-3-arylpropan-1-ones. Condensation of 1-(5-nitro-2-furyl)-2-bromo-3-aryl-2-propen-1-ones with 4-amino-5- mercapto-1, 2, 4-triazoles afforded a new class of 6-(5-nitro-2-furyl)-7-arylidene-1, 2, 4- triazolo [3, 4-b]-1, 3, 4-thiadiazines. The structure of the condensation products are fully ...