Haval–Argade contrathermodynamic rearrangement of alkylidenesuccinimides to alkylmaleimides via the corresponding isoimides: a general approach to alkyl and …
KP Haval, NP Argade
Index: Haval, Kishan P.; Argade, Narshinha P. Tetrahedron, 2006 , vol. 62, # 15 p. 3557 - 3563
Full Text: HTML
Citation Number: 19
Abstract
A simple and efficient access to alkyl and dialkyl substituted maleimides has been demonstrated via the new contrathermodynamic rearrangement of (E)- alkylidenesuccinimides to alkylmaleimides. The (E)-alkylidenesuccinimides obtained from the Wittig-condensation of N-arylmaleimide with aliphatic aldehydes on regioselective hydrolysis furnished the corresponding (E)-alkylidenesuccinanilic acids in 95–98% yields. ...
Related Articles:
Reaction mechanism between pyruvic acid and aromatic amines.
[Tapia, I.; Alcazar, V.; Moran, J. R.; Grande, M. Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 8 p. 2408 - 2413]