Synthesis of β-fluoroalkyl phenyl (or methyl) thioethers by sulfur-assisted halogen exchange with triethylamine tris-hydrofluoride
C Saluzzo, G Alvernhe, D Anker, G Haufe
Index: Saluzzo, C.; Alvernhe, G.; Anker, D.; Haufe, G. Journal of Fluorine Chemistry, 1990 , vol. 47, # 3 p. 467 - 479
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Citation Number: 11
Abstract
Abstract The exchange of chlorine in β-chloroalkyl phenyl (or methyl) thioethers by fluorine, with anchimeric assistance of sulfur, is very easily realized with the almost neutral fluorinating reagent, Et 3 N. 3HF. The 'one-pot'reactions of alkenes with sulfenyl chlorides and subsequently with Et 3 N. 3HF lead to the corresponding β-fluoroalkyl thioethers in high yields.
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