A concise synthesis of functionalised gem-difluoroalkenes, via the addition of organolithium reagents to α-trifluoromethylstyrene
JP Bégué, D Bonnet-Delpon, MH Rock
Index: Begue, Jean-Pierre; Bonnet-Delpon, Daniele; Rock, Michael H. Tetrahedron Letters, 1995 , vol. 36, # 28 p. 5003 - 5006
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Citation Number: 33
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The treatment of α-trifluoromethyl styrene with organolithium reagents results in the selective formation of gem-difluoroalkenes in good to excellent yield. This reaction has been applied to the synthesis of a range functionalised gem-difluoroalkenes.
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