A clean and efficient cyclocondensation to pyrido [2, 3-d] pyrimidine derivatives in aqueous media
R Baharfar, R Azimi
Index: Baharfar, Robabeh; Azimi, Razieh Chinese Chemical Letters, 2011 , vol. 22, # 10 p. 1183 - 1186
Full Text: HTML
Citation Number: 10
Abstract
A series of pyrido [2, 3-d] pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6-aminothiouracil with α, β-unsaturated carbonyl compounds (aldehyde, ketone and ester) possessing a leaving group on the β position, in H2O under reflux conditions.
Related Articles:
A simple synthesis of 1, 3-dialkylpyrido [2, 3-d] pyrimidines
[Itoh, Tsuneo; Imini, Toshihiko; Ogura, Haruo; Kawahara, Norio; Nakajima, Takako; et al. Heterocycles, 1983 , vol. 20, # 11 p. 2177 - 2180]
[Hirota, Kosaku; Kubo, Keiko; Sajiki, Hironao; Kitade, Yukio; Sako, Magoichi; Maki, Yoshifumi Journal of Organic Chemistry, 1997 , vol. 62, # 9 p. 2999 - 3001]
A simple synthesis of 1, 3-dialkylpyrido [2, 3-d] pyrimidines
[Itoh, Tsuneo; Imini, Toshihiko; Ogura, Haruo; Kawahara, Norio; Nakajima, Takako; et al. Heterocycles, 1983 , vol. 20, # 11 p. 2177 - 2180]