Synlett

A new efficient palladium catalyst for the amination of aryl chlorides

U Nettekoven, F Naud, A Schnyder, HU Blaser

Index: Nettekoven, Ulrike; Naud, Frederic; Schnyder, Anita; Blaser, Hans-Ulrich Synlett, 2004 , # 14 p. 2549 - 2552

Full Text: HTML

Citation Number: 10

Abstract

Abstract A highly active catalyst for the Buchwald-Hartwig amination has been developed. The new catalyst, a combination of a dimethylaminomethyl ferrocene palladacycle and bis (2- norbornyl) phosphine shows high activity and broad scope for the coupling of non-or deactivated aryl chlorides with primary and secondary amines as well as (hindered) anilines.