Tetrahedron letters

Synthesis of diacetylenic analogues of leukotriene A 4 (LTA 4) methyl ester

JP Lellouche, J Deschamps, C Boullais, JP Beaucourt

Index: Lellouche; Deschamps; Boullais; Beaucourt Tetrahedron Letters, 1988 , vol. 29, # 25 p. 3073 - 3076

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Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Methyl (5S,6S)-epoxy-11,14-eicosadiyne-7E,9E-dienoate 1 and its 7Z isomer 2 were prepared using Wittig methodology. 1 did not inhibit human neutrophil 5-lipoxygenase but rather stimulated LTB 4 formation. ... Methyl (5S,6S)-epoxy-11,14-eicosadiyne-7E,9E-dienoate1 and its 7Z ...

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