Some synthetic applications of 2, 3-Dichloro-N-phenylmaleimide: A Novel Synthesis of 2-Phenylpyrrolo [3, 4-b] quinoxaline-1, 3-diones. I
L Hanaineh-Abdelnour, S Bayyuk, R Theodorie
Index: Hanaineh-Abdelnour, Leila; Bayyuk, Shibly; Theodorie, Rima Tetrahedron, 1999 , vol. 55, # 40 p. 11859 - 11870
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Citation Number: 23
Abstract
2, 3-Dichloro-N-phenylmaleimide 2 undergoes nucleophilic substitution reactions by a variety of nucleophiles giving either monosubstituted 5 or disubstituted 3 products. Treatment of 5 with sodium azide at room temperature results in cyclization to the corresponding 2-phenylpyrrolo [3, 4-b] quinoxaline-1, 3-diones 6, while at higher temperatures 5 is reduced to the 2-amino-3-amino-N-phenylmaleimides7.
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