Diastereoselective Hydroformylation of 2??Substituted Allylic o??DPPB??Esters—On the Origin of 1, 2??Asymmetric Induction

B Breit, G Heckmann, SK Zahn

Index: Breit, Bernhard; Heckmann, Golo; Zahn, Stephan K. Chemistry - A European Journal, 2003 , vol. 9, # 2 p. 425 - 434

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Citation Number: 18

Abstract

Abstract 2-Substituted secondary alcohol o-DPPB esters (o-DPPB= ortho- diphenylphosphanylbenzoyl) have been prepared and their o-DPPB-directed diastereoselective hydroformylation examined. It was found that the diastereoselectivity increased as a function of the steric demand of the substituents both at the stereogenic center and in the alkene 2-position. Hydrolytic cleavage of the o-DPPB group afforded— ...