Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H-and 11Me-indolo [3, 2-c] quinolines

…, K Imai, TA Ngoc, CQ Pang, L Wang, J Wietrzyk…

Index: Wang, Ning; Switalska, Marta; Wu, Ming-Yu; Imai, Kento; Ngoc, Tran Anh; Pang, Cui-Qing; Wang, Li; Wietrzyk, Joanna; Inokuchi, Tsutomu European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 314 - 323

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Citation Number: 10

Abstract

Abstract A series of 6-amino-11H-indolo [3, 2-c] quinoline derivatives with various substituents on the quinoline ring were synthesized. A methyl group introduced to N-11 of the intermediate 4 to elaborate novel analog 7. The cytotoxic effect of these 6-amino- ...