Environmentally friendly and efficient process for the preparation of β-hydroxyl ketones
GW Wang, Z Zhang, YW Dong
Index: Wang, Guan-Wu; Zhang, Ze; Dong, Ya-Wei Organic Process Research and Development, 2004 , vol. 8, # 1 p. 18 - 21
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Citation Number: 31
Abstract
An environmentally benign and efficient process for the preparation of β-hydroxyl ketones was developed by the practical cross-aldol reactions of 2-acetylpyridine, acetophenone, and cyclohexanone with 4-nitro-, 3-nitro-, and 2-nitrobenzaldehydes in water catalyzed by Na2CO3 in very high yields.
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