Chiral Macrocyclic Bis (oxazoline) CuI Complexes–Structure/Stereoselectivity Relationships in Catalytic Cyclopropanations

T Portada, M Roje, Z Raza, V Čaplar…

Index: Portada, Tomislav; Roje, Marin; Raza, Zlata; Caplar, Vesna; Zinic, Mladen; Sunjic, Vitomir European Journal of Organic Chemistry, 2007 , # 5 p. 838 - 856

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Citation Number: 6

Abstract

Abstract The design and synthesis of 18 chiral macrocycles with built in C 2-symmetric bis (oxazoline) units is described and the catalytic properties of their copper (I) complexes in cyclopropanations of styrene with ethyl diazoacetate are assessed. The bridging of two homochiral centers in the bis (oxazoline) unit gives a macrocyclic ligand, which upon binding of Cu I is transformed into a macrocyclic catalytic complex containing a chiral ...