Formation of a chiral 1-fluoro-2, 2-diphenylcyclopropyl radical in the Barton decarboxylation reaction

K Gawronska, J Gawronski…

Index: Gawronska, K.; Gawronski, J.; Walborsky, H. M. Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2193 - 2197

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Citation Number: 24

Abstract

The thermal decomposition of N-hydroxypyridine-2-thione esters to produce radicals which can react with a variety of halogen-donating reagents resulting in an halogenative decarboxylation reaction or with H-atom donating sources to give rise to products of decarboxylation has been given the appellation, Barton decarboxylation reaction. 2 In an ancillary study the need arose to prepare chiral l-bromo-l-fluoro-2, 2- ...