Synthesis and structure-affinity relationships of 1-[ω-(4-aryl-1-piperazinyl) alkyl]-1-aryl ketones as 5-HT7 receptor ligands

R Perrone, F Berardi, NA Colabufo…

Index: Journal of Medicinal Chemistry, , vol. 46, # 4 p. 646 - 649

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Citation Number: 51

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The preparation of the final compounds (Scheme 1) required the key intermediate ω-haloalkylphenyl ketones 9−22. Derivatives 9−12 were prepared from benzaldehydes ...