Tetrahedron

An efficient conversion of nitroaromatics and aromatic amines to tertiary amines in one-pot way

YJ Jung, JW Bae, ES Park, YM Chang, CM Yoon

Index: Jung, Yeon Joo; Bae, Jong Woo; Park, Eun Soo; Chang, Yu Mi; Yoon, Cheol Min Tetrahedron, 2003 , vol. 59, # 51 p. 10331 - 10338

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Citation Number: 18

Abstract

Reductive alkylation and reductive methylation of aromatic primary amines with carbonyls and 37% formaldehyde using decaborane in one-pot way gave the corresponding tertiary amines in high yields. The reaction condition was extended for the reduction of nitroaromatic using decaborane and Pd/C followed by the reductive alkylation and reductive methylation using decaborane to give the corresponding tertiary amines in high yields.

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