Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity. sigma. ligands

…, AM Ismaiel, MB El-Ashmawy, JL Herndon…

Index: Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie Journal of Medicinal Chemistry, 1991 , vol. 34, # 12 p. 3360 - 3365

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Citation Number: 44

Abstract

Department of Medicinal Chemistry, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298-0540, and Cambridge NeuroScience Research, Cambridge, Massachusetts 02139. Received April 18, 1991 u receptors may represent an exciting new approach for the development of novel psychotherapeutic agents. Unfortunately, many of the commonly used u ligands lack ...