Synthetic connections to the aromatic directed metalation reaction. Functionalized aryl boronic acids by ipso borodesilylation. General syntheses of unsymmetrical …
MJ Sharp, W Cheng, V Snieckus
Index: Sharp, M. J.; Cheng, W.; Snieckus, V. Tetrahedron Letters, 1987 , vol. 28, # 43 p. 5093 - 5096
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Citation Number: 152
Abstract
Abstract Aryl boronic acids 2a-d and 4a-d obtained by metalation-B (OMe) 3 or metalation silylation-ipso borodesilylation sequences, participate in efficient Pd-catalyzed cross coupling reactions with aryl bromides to give unsymmetrical biphenyls 3a-d and Full-size image (< 1 K)
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