Journal of the American Chemical Society

A new tributyltin hydride-based rearrangement of bromomethyl. beta.-keto esters. A synthetically useful ring expansion to. gamma.-keto esters

P Dowd, SC Choi

Index: Dowd, Paul; Choi, Soo-Chang Journal of the American Chemical Society, 1987 , vol. 109, # 11 p. 3493 - 3494

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Citation Number: 150

Abstract

The universal presence of five-and six-membered ring ketones among organic molecules has made the Dieckmann condensation'a central ring-forming reaction in organic chemistry. The utility of the Dieckmann condensation is further enhanced by the alkylation- decarboxylation sequence leading to a virtually limitless variety of a-substituted cyclopentanones and cyclohexanones. Any additional flexibility that serves to enlarge the ...