New total synthesis of (.+-.)-indolmycin

JP Dirlam, DA Clark, SJ Hecker

Index: Dirlam, John P.; Clark, David A.; Hecker, Scott J. Journal of Organic Chemistry, 1986 , vol. 51, # 25 p. 4920 - 4924

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Citation Number: 28

Abstract

11 work in construction of the oxazolone ring at a late stage in the synthesis? & In addition, this approach would make possible the synthesis of benzo-substituted analogues not readily available via the published procedures, and would also allow preparation of 2-amino analogues of the parent antibiotic via the amine exchange reaction.