The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

SD Barrett, AJ Bridges, DT Dudley, AR Saltiel…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 24 p. 6501 - 6504

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Citation Number: 164

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... The goal of the medicinal chemistry program was to identify lead matter that possesses in vivo activity when administered orally in an animal model. ...