Synthesis of benzyl (6S)-1, 3-dichloro-4-oxo-4, 6, 7, 8-tetrahydro-pyrrolo [1, 2-a] pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic …
P Gloanec, Y Hervé, N Brémand, JP Lecouvé…
Index: Gloanec, Philippe; Herve, Yolande; Bremand, Nathalie; Lecouve, Jean-Pierre; Breard, Fabienne; De Nanteuil, Guillaume Tetrahedron Letters, 2002 , vol. 43, # 19 p. 3499 - 3501
Full Text: HTML
Citation Number: 11
Abstract
We describe the synthesis of benzyl (6S)-1, 3-dichloro-4-oxo-4, 6, 7, 8-tetrahydro-pyrrolo [1, 2-a] pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic derivative. This compound is prepared in seven steps from (S)-pyroglutamic acid as starting material.
Related Articles:
[Aggarwal, Varinder K.; Astle, Christopher J.; Rogers-Evans, Mark Organic Letters, 2004 , vol. 6, # 9 p. 1469 - 1471]
[Aggarwal, Varinder K.; Astle, Christopher J.; Rogers-Evans, Mark Organic Letters, 2004 , vol. 6, # 9 p. 1469 - 1471]
[Aggarwal, Varinder K.; Astle, Christopher J.; Rogers-Evans, Mark Organic Letters, 2004 , vol. 6, # 9 p. 1469 - 1471]