Regio-and stereospecific uncatalyzed reactions of electron-rich arenes and olefins at organomolybdenum enantiomeric scaffolds

W Chen, K Sana, Y Jiang, EVS Meyer, S Lapp…

Index: Chen, Wenyong; Sana, Kasinath; Jiang, Yi; Meyer, Esmerelda V. S.; Lapp, Stacey; Galinski, Mary R.; Liebeskind, Lanny S. Organometallics, 2013 , vol. 32, # 24 p. 7594 - 7611

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Abstract

A novel uncatalyzed reaction between TpMo (CO) 2 (5-trifluoroacetoxy-η3-5, 6- dihydropyranyl/dihydropyridinyl) complexes and electron-rich arenes/olefins is reported. The reaction proceeds under mild reaction conditions so that a variety of functional groups are tolerated. Combined with a stereospecific annulative demetalation, the new reaction provides a rapid access to polycyclic alkaloid structures. The sequential protocol was ...

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