Identification of Vimentin Binding to the Derivative of Saurolactam with Antiresorptive Activity by Using Its Chemical Affinity Probe

MH Kim, YL Choi, JN Heo, YK Min…

Index: Kim, Myung Hee; Choi, Young Lok; Heo, Jung-Nyoung; Min, Yong Ki; Kim, Seong Hwan Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 7 p. 2047 - 2050

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Abstract

Figure 1.(A) Structures of saurolactam (7) and its derivative (7a) with antiresorptive activity.(B) Effect of 7aon the RANKL-induced TRAP activity in RAW264. 7 cells was evaluated as described in reference 7.***, p< 0.001 (C) Effect of 7aon the formation of MNCs was evaluated by TRAP staining method.

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