A short synthesis of two chiral anthracycline AB synthons
HL Holland, P Viski
Index: Holland, Herbert L.; Viski, Peter Journal of Organic Chemistry, 1991 , vol. 56, # 17 p. 5226 - 5229
Full Text: HTML
Citation Number: 9
Abstract
An alternative approach to the asymmetric synthesis of anthracyclines has been to construct an AB synthon such as 7 or 11 that possesses all the necessary chirality. Molecules of this type are currently only available by lengthy procedures involving a chiral precursor such as a carbohydrateg or via resolution of a synthetic intermediate. 1 We now report a short and efficient synthesis of chiral anthracycline AB synthons both with (7) and without (5) the ...
Related Articles:
Baker's yeast mediated reduction of aromatic ring substituted 2-tetralones
[Manitto, Paolo; Speranza, Giovanna; Monti, Diego; Fontana, Gabriele; Panosetti, Elisa Tetrahedron, 1995 , vol. 51, # 42 p. 11531 - 11546]
Baker's yeast mediated reduction of aromatic ring substituted 2-tetralones
[Perez; Rosell; Mauleon; Carganico Farmaco, 1991 , vol. 46, # 10 p. 1155 - 1166]
[Tririya, Gasirat; Zanger, Murray Synthetic Communications, 2004 , vol. 34, # 17 p. 3047 - 3059]
[Tririya, Gasirat; Zanger, Murray Synthetic Communications, 2004 , vol. 34, # 17 p. 3047 - 3059]
[Tririya, Gasirat; Zanger, Murray Synthetic Communications, 2004 , vol. 34, # 17 p. 3047 - 3059]