Monophthalates with oxidized C5-carbon in the ester chain: a simple synthetic access to two major metabolites of bis-(2-ethylhexyl)-phthalate

HD Gilsing, J Angerer, D Prescher

Index: Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155

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Citation Number: 23

Abstract

Summary. The synthesis of two oxidized metabolites of bis-(2-ethylhexyl)-phthalate is described. The target structures were obtained by esterification of the appropriate alcohol carrying a protected hydroxy group with phthalic anhydride, followed by deprotection and further oxidation.