6??Amino??3??Pyridinols: Towards Diffusion??Controlled Chain??Breaking Antioxidants

…, L Valgimigli, GA DiLabio, GF Pedulli…

Index: Wijtmans, Maikel; Pratt, Derek A.; Valgimigli, Luca; DiLabio, Gino A.; Pedulli, Gian Franco; Porter, Ned A. Angewandte Chemie - International Edition, 2003 , vol. 42, # 36 p. 4370 - 4373

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Citation Number: 131

Abstract

LOOC ArOH kinh É! LOOH ArOC 2fi propagation (kp [LH]). The best-known example of a phenolic antioxidant is α-tocopherol (α-TOH, 2), the most potent form of vitamin E, nature's primary defense against radical chain oxidation.[1] Recently, considerable effort has been devoted to the development of peroxyl-radical-trapping antioxidants more effective than α- TOH,[2–5] since the peroxidation of lipids in vivo has been suggested to be a major factor ...