Stereoselective synthesis of (2s, 3s, 4r)-4-amino-3-hydroxy-2-methyl-pentanoic acid, an amino acid constituent of bleomycin, by aldold condensation)

M Narita, M Otsuka, S Kobayashi, M Ohno…

Index: Narita, Masatoshi; Otsuka, Masami; Kobayashi, Susumu; Ohno, Masaji Tetrahedron Letters, 1982 , vol. 23, # 5 p. 525 - 528

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Citation Number: 29

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... (2S,3S,4R)-4-Amino-3-hydroxy-2-methylpentanoic acid, a novel amino acid constituent of bleomycin, has been synthesized stereoselectively through aldol condensation of (R)-2-aminopropionaldehyde derivatives and E-vinyloxyboranes. ... Tetrahedron Lett. (1979), p. 3937 and references ...

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