Tetrahedron

Desulfurization of epidithio-2, 5-piperazinedione derivatives and their open chain analogs with triphenyl phosphine

T Sato, T Hino

Index: Sato,T.; Hino,T. Tetrahedron, 1976 , vol. 32, p. 507 - 513

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Citation Number: 15

Abstract

Desulfurization of epidithio-2, 5-piperazinediones (6 and 7) by triphenylphosphine in THF gave dimeric compounds (8 and 15). In the presence of water or phenol the desulfurization gave 3-hydroxy (9) or 3-phenoxy-2, 5-piperazinedione (10). Reaction of 6c with triphenylphosphine in ethyl vinyl ether yielded 2, 5-diazabicyclo [2.2. 2] octane-3, 6-dione (11), indicating the presence of 1, 4-dipole (B) as an intermediate of the desulfurization. ...