A Re??Examination of the Reaction of 3, 4??Diamino [1, 2, 5] oxadiazole with Glyoxal

…, CG Campbell, SW Bunte, D Parrish

Index: Willer, Rodney L.; Storey, Robson F.; Campbell, Christopher G.; Bunte, Steven W.; Parrish, Damon Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 919 - 925

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Abstract

Abstract Reaction coordinate mapping was used to study the reaction of 3, 4-diamino [1, 2, 5] oxadiazole (3, 4-diaminofurazan) and 3, 4-diamino [1, 2, 5] thiadiazole with glyoxal. The thiadiazole was known to give a good yield of [1, 2, 5] thiadiazolo [3, 4-b] pyrazine, whereas the oxadiazole had not yielded, until now,[1, 2, 5] oxadiazolo [3, 4-b] pyrazine (or furazano [2, 3-b] pyrazine). The calculations suggested that the diols, 5, 6-dihydroxy-4, 5, 6, 7- ...