Unusually facile palladium catalysed oxidation of imidazolidines and oxazolidines

A Alexakis, I Aujard, J Pytkowicz, S Roland…

Index: Alexakis; Aujard; Pytkowicz; Roland; Mangeney Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 949 - 951

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Citation Number: 6

Abstract

A possible route for such an epimerisation, could be to take advantage of the benzylic position and to use a transition metal, the most obvious being palladium. When aminal 2 was treated with 10% Pd(OH) 2 , in i-PrOH, under a hydrogen atmosphere, a rapid reaction took place, and, within 6 h at room temperature, all of the starting material disappeared in favor of a new very polar compound. This new compound was the monoformamide 3 of the starting ...