Synthesis of 1, 1′, 2, 2′, 3, 3′, 4, 4′??octadeutero??sulforaphane

N Kuhnert, Y Lu

Index: Kuhnert, Nikolai; Lu, Ye Journal of Labelled Compounds and Radiopharmaceuticals, 2004 , vol. 47, # 8 p. 501 - 507

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Abstract

Abstract Sulforaphane (SFN), a naturally occurring isothiocyanate present in broccoli, shows strong evidence of anti-carcinogenic activity. The mechanism of action, absorption, distribution, metabolism and excretion of the compound is however still poorly understood and requires a stable isotope labelled version of the compound for further studies. The paper describes an optimized synthesis of octadeutero-SFN. Copyright© 2004 John Wiley ...