Synthesis of novel vitamin C phosphodiesters: stability and antioxidant activity

K Morisaki, S Ozaki

Index: Morisaki, Kazuo; Ozaki, Shoichiro Carbohydrate Research, 1996 , vol. 286, p. 123 - 138

Full Text: HTML

Citation Number: 15

Abstract

A novel series of hybrid l-ascorbic acid (vitamin C) phosphodiesters linked at the C-2 hydroxyl group with other biologically active substances, namely myo-inositol, arbutin, 4- hydroxy-l-proline, and glycolic acid were synthesized, and their thermal stability and reducing activity against free radicals were estimated in vitro. All of the phosphodiesters exhibited high thermal stabilities; however, their antioxidant activities in vitro were ...