Luminescent ruthenium (II) polypyridyl functionalized gold nanoparticles; their DNA binding abilities and application as cellular imaging agents

…, DC Williams, T Gunnlaugsson

Index: Elmes, Robert B. P.; Erby, Marialuisa; Cloonan, Suzanne M.; Quinn, Susan J.; Williams, D. Clive; Gunnlaugsson, Thorfinnur Chemical Communications, 2011 , vol. 47, # 2 p. 686 - 688

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Citation Number: 76

Abstract

The synthesis and photophysical and biological investigation of Ru (II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h.