Transition metal-free synthesis of primary amides from aldehydes and hydroxylamine hydrochloride
W Wang, XM Zhao, JL Wang, X Geng, JF Gong…
Index: Wang, Wei; Zhao, Xue-Mei; Wang, Jing-Li; Geng, Xin; Gong, Jun-Fang; Hao, Xin-Qi; Song, Mao-Ping Tetrahedron Letters, 2014 , vol. 55, # 20 p. 3192 - 3194
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Citation Number: 5
Abstract
Abstract Primary aromatic amides can be synthesized from aldehydes and hydroxylamine hydrochloride in the presence of Cs 2 CO 3. Various aromatic aldehydes (include some heteroaromatic aldehydes) are able to generate the corresponding aromatic amides in moderate to excellent yields.
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