Organic letters

Synthesis of 7-substituted benzolactam-V8s and their selectivity for protein kinase C isozymes

D Ma, G Tang, AP Kozikowski

Index: Endo, Yasuyuki; Takehana, Shunji; Ohno, Michihiro; Driedger, Paul E.; Stabel, Silvia; Mizutani, Miho Y.; Tomioka, Nobuo; Itai, Akiko; Shudo, Koichi Journal of Medicinal Chemistry, 1998 , vol. 41, # 9 p. 1476 - 1496

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Citation Number: 29

Abstract

... of diastereomers 13 and 14 (Scheme 2). 12 The undesired isomer 14 was converted to thermodynamically stable 13 by ... (c) Stabel, S.; Parker, PJ ... CAS] Therapeutic potential of protein kinase C inhibitors. Bradshaw, David; Hill, Christopher H.; Nixon, John S.; Wilkinson, Sandra ...