Reactions of 2, 2-dibromocyclopropyl carboxylic acids with methyllithium

LK Sydnes, S Skare

Index: Sydnes, Leiv K.; Skare, Soelvi Canadian Journal of Chemistry, 1984 , vol. 62, p. 2073 - 2078

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Citation Number: 19

Abstract

For reactions of 2, 2-dibromocyclopropyl carboxylic acids with methyllithium, the course of reaction depends mainly on the position of the carboxyl group. When the COOH group is directly attached to the gem-dibromocyclopropane ring MeLi generally attacks the gem- dibromo moiety and gives the corresponding monobromocyclopropane as the principal product. When the reaction is performed above-80° C the monobromides are formed ...