Regioselective reductions of various 3-aminosuccinimides; Application to the synthesis of two heterocyclic systems
…, P Charpentier, G Dupas, G Quéguiner, J Bourguignon
Index: Briere, Jean-Francois; Charpentier, Patricia; Dupas, Georges; Queguiner, Guy; Bourguignon, Jean Tetrahedron, 1997 , vol. 53, # 6 p. 2075 - 2086
Full Text: HTML
Citation Number: 31
Abstract
The synthesis of novel pyrrolo [3, 2-c] isoquinolines is investigated starting from 3- aminosuccinimides. Various known routes leading to 3-aminosuccinimides were tested but a new approach via nucleophilic addition of arylalkylamines on maleimide gave better results. The regioselectivity of the reduction of these compounds was shown to depend on the degree of substitution of the concerned 3-aminosuccinimide. The hydroxylactams are ...
Related Articles:
[Bell, Ian M.; Gallicchio, Steven N.; Abrams, Marc; Beese, Lorena S.; Beshore, Douglas C.; Bhimnathwala, Hema; Bogusky, Michael J.; Buser, Carolyn A.; Culberson, J. Christopher; Davide, Joseph; Ellis-Hutchings, Michelle; Fernandes, Christine; Gibbs, Jackson B.; Graham, Samuel L.; Hamilton, Kelly A.; Hartman, George D.; Heimbrook, David C.; Homnick, Carl F.; Huber, Hans E.; Huff, Joel R.; Kassahun, Kelem; Koblan, Kenneth S.; Kohl, Nancy E.; Lobell, Robert B.; Lynch Jr., Joseph J.; Robinson, Ronald; Rodrigues, A. David; Taylor, Jeffrey S.; Walsh, Eileen S.; Williams, Theresa M.; Zartmant, C. Blair Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2388 - 2409]
[Banfi, Luca; Basso, Andrea; Giardini, Lorenzo; Riva, Renata; Rocca, Valeria; Guanti, Giuseppe European Journal of Organic Chemistry, 2011 , # 1 p. 100 - 109]
[Banfi, Luca; Basso, Andrea; Giardini, Lorenzo; Riva, Renata; Rocca, Valeria; Guanti, Giuseppe European Journal of Organic Chemistry, 2011 , # 1 p. 100 - 109]
[Banfi, Luca; Basso, Andrea; Giardini, Lorenzo; Riva, Renata; Rocca, Valeria; Guanti, Giuseppe European Journal of Organic Chemistry, 2011 , # 1 p. 100 - 109]