The Journal of Organic Chemistry

Direct preparation of 3-thienyl organometallic reagents: 3-thienylzinc and 3-thienylmagnesium iodides and 3-thienylmanganese bromides and their coupling reactions

RD Rieke, SH Kim, X Wu

Index: Rieke, Reuben D.; Kim, Seung-Hoi; Wu, Xiaoming Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6921 - 6927

Full Text: HTML

Citation Number: 64

Abstract

3-Thienylzinc and 3-thienylmagnesium iodides can be generated from the direct oxidative addition of Rieke zinc and magnesium to 3-iodothiophene, respectively. The direct preparation of 3-thienylmanganese bromides from the reaction of Rieke manganese with 3- bromothiophene and 3, 4-dibromothiophene is also performed. These 3-thienyl organometallic reagents have been found to be regiostable intermediates and undergo ...