Highly Substituted Aromatics. The Synthesis and Nuclear Magnetic Resonance Spectrum of 2, 4, 6-Tri-t-butyl-3-fluorophenol1

B Rickborn, DA May, AA Thelen

Index: Rickborn,B. et al. Journal of Organic Chemistry, 1964 , vol. 29, p. 91 - 93

Full Text: HTML

Citation Number: 3

Abstract

The low steric requirements of the fluoro substituent allow the insertion of a t-butyl group in the 2-position of 3-fluorophenol, aa evidenced by the preparation of the title compound. The nmr spectra of this material and some analogs were used for structure proof; long-range HF spin-spin coupling between the protons of the 2-and 4-t-butyl groups and the adjacent fluorine was observed.