The Journal of Organic Chemistry

Notes-Nitrogen Mustard Derivatives of Phenothiazine and Phenoxazine

D Shirley, K Sen, J Gilmer

Index: Shirley,D.A. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 3587 - 3588

Full Text: HTML

Citation Number: 12

Abstract

EXPERIMENTAL3 20-(2€ hlo~ oe~ hyl) phenosazine. A solution (45 ml.) of 0.068 mole of n- butyllithium in mixed pentane-heptane solvent (Foote Mineral Co. product) nas added gradually (nitrogen atmosphere) tc a solution of 11.5 g.(0.063 mole) of phenoxa-zinc'in 75 nil. of dry benzene. The mixture was stirred for 30 min. during which time a yellow-red precipitste of N-lithiophenoxazine appeared. The resulting slurry was added to a solution ...