Mercury (II)-mediated cleavage of cyclopropylcarbinols by an intramolecular sulfinyl group as a stereo-and regioselective route to stereotriads and stereotetrads

S Raghavan, V Sudheer Babu…

Index: Raghavan, Sadagopan; Sudheer Babu, Vaddela; Sridhar Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 557 - 565

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Citation Number: 4

Abstract

Mercury (II) salt mediated opening of cyclopropylcarbinols by an intramolecular sulfinyl group is disclosed. All four diastereomeric stereotriads have been prepared from cis-and trans-disubstituted cyclopropanes. The trisubstituted cyclopropanes also react regio-and stereoselectively to afford products possessing quaternary stereogenic centers. The reaction is clean and general.